(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanedioic acid
N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Glutamic Acid
CAS: 104091-09-0
Molecular Formula: C20H19NO6
(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanedioic acid - Names and Identifiers
| Name | N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Glutamic Acid |
| Synonyms | Fmoc-D-Glu-OH Fmoc-D-glutamic acid Fmoc-D-glutamic acid N-FMOC-D-GLUTAMIC ACID N-Fmoc-D-glutamic acid N-Fmoc-D-glutamic AcidFmoc-D-Glu-OH (9H-Fluoren-9-yl)MethOxy]Carbonyl D-Glu-OH N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-glutamic Acid N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Glutamic Acid (((9H-fluoren-9-yl)methoxy)carbonyl)-D-glutamic acid N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-D-GLUTAMIC ACID (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanedioic acid (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanedioic acid |
| CAS | 104091-09-0 |
| InChI | InChI=1/C20H19NO6/c22-18(23)10-9-17(19(24)25)21-20(26)27-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16-17H,9-11H2,(H,21,26)(H,22,23)(H,24,25)/t17-/m1/s1 |
(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanedioic acid - Physico-chemical Properties
| Molecular Formula | C20H19NO6 |
| Molar Mass | 369.37 |
| Density | 1.366±0.06 g/cm3(Predicted) |
| Boling Point | 635.8±50.0 °C(Predicted) |
| Flash Point | 338.311°C |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | powder to crystal |
| Color | White to Almost white |
| pKa | 3.72±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 19 ° (C=1, DMF) |
(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanedioic acid - Introduction
Fmoc-D-Glutamic acid is a chemical reagent, which is widely used in peptide synthesis and protein analysis in chemical synthesis.
The nature of Fmoc-D-glutamic acid is a white crystalline solid with a molecular weight of 374.4. It is an unnatural amino acid, the D isomer of glutamic acid. Fmoc-D-glutamic acid has good solubility and can be dissolved in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
The main use of Fmoc-D-glutamic acid is the introduction of amino acid units in polypeptide synthesis. It can be combined with other amino acids into a polypeptide chain by methods such as solid phase synthesis or liquid phase synthesis. The synthesis of polypeptide chains is an important tool for studying the function and structure of proteins. In addition, Fmoc-D-glutamic acid can also be used for drug candidate screening and drug delivery system construction in drug development.
The production method of Fmoc-D-glutamic acid is usually obtained by chemical synthesis. Specifically, Fmoc-D-glutamic acid can be synthesized by binding a D-form isomer of glutamic acid to an Fmoc protecting group. The synthetic steps include reaction, purification and crystallization, etc.
When using Fmoc-D-glutamic acid, it is necessary to pay attention to its safety. It is a chemical reagent, so laboratory safety procedures should be followed. Avoid contact with skin and eyes, wear protective gloves and goggles if necessary. At the same time, store it in a dry, cool place to avoid contact with oxidants and combustibles. If inhaled or ingested, seek medical assistance immediately.
The nature of Fmoc-D-glutamic acid is a white crystalline solid with a molecular weight of 374.4. It is an unnatural amino acid, the D isomer of glutamic acid. Fmoc-D-glutamic acid has good solubility and can be dissolved in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.
The main use of Fmoc-D-glutamic acid is the introduction of amino acid units in polypeptide synthesis. It can be combined with other amino acids into a polypeptide chain by methods such as solid phase synthesis or liquid phase synthesis. The synthesis of polypeptide chains is an important tool for studying the function and structure of proteins. In addition, Fmoc-D-glutamic acid can also be used for drug candidate screening and drug delivery system construction in drug development.
The production method of Fmoc-D-glutamic acid is usually obtained by chemical synthesis. Specifically, Fmoc-D-glutamic acid can be synthesized by binding a D-form isomer of glutamic acid to an Fmoc protecting group. The synthetic steps include reaction, purification and crystallization, etc.
When using Fmoc-D-glutamic acid, it is necessary to pay attention to its safety. It is a chemical reagent, so laboratory safety procedures should be followed. Avoid contact with skin and eyes, wear protective gloves and goggles if necessary. At the same time, store it in a dry, cool place to avoid contact with oxidants and combustibles. If inhaled or ingested, seek medical assistance immediately.
Last Update：2024-04-09 21:11:58
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